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Lion's Mane, Reishi, Shiitake, Cordyceps & Maitake

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Source of antioxidants that help protect cells against the oxidative damage caused by free radicals

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Help increase energy resistance to stress and support the immune system

NovoMune - Mushroom Synergy 

Source of antioxidants that help protect cells against the oxidative damage caused by free radicals. Source of fungal polysaccharides with immunomodulating properties.

 

Used in herbal medicine as a liver tonic. Use in Herbal Medicine as an adaptogen to help increase energy resistance to stress and support the immune system. Used in Traditional Chinese Medicine (TCM) to dispel phlegm stop cough and arrest wheezing.

 

Used in TCM to nourish the heart and strengthen qi and blood to treat heart and spleen deficiencies that manifest in insomnia, forgetfulness, fatigue, listlessness and poor appetite. Used in TCM to strengthen the body and tonify qi.

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About NovoMune :

Anti-inflammatory
Anti-oxidative
Support Immune System Efficiency
Anti-cholesterol
Fertility enhancer

Improves Appearance of Skin 

Sleep-promoting

Novomune Mushroom Synergy is available in 60 capsules

More Information

Recommended Use

Source of antioxidants that help protect cells against the oxidative damage caused by free radicals. Source of fungal polysaccharides with immunomodulating properties. Used in herbal medicine as a liver tonic. Use in Herbal Medicine as an adaptogen to help increase energy resistance to stress and support the immune system.Used in Traditional Chinese Medicine (TCM) to dispel phlegm stop cough and arrest wheezing.Used in TCM to nourish the heart and strengthen qi and blood to treat heart and spleen deficiencies that manifest in insomnia, forgetfulness, fatigue, listlessness and poor appetite. Used in TCM to strengthen the body and tonify qi.

 

Recommended Dose

Adults 18 years and older: 1 Capsule per day. Take with food/meal to avoid digestive upset.

Lion's Mane

Mushrooms are generally a good source of nutrients and health-promoting compounds.1−3 More than 2000 species of edible and medicinal mushrooms have been identified.

 

Among these, the culinary & medicinal Hericium erinaceous, also known as Lion's Mane, has the potential to help prevent, alleviate, or treat significant diseases, including cancer,depression, diabetes, lipidemia, and neurodegenerative diseases (9) Over the past decade, it has been demonstrated that H. erinaceous polysaccharides possess various promising bioactivities, including antitumor and immunomodulation, anti-gastric ulcer, neuroprotection, and neuroregeneration, anti-oxidation and hepatoprotection, anti-hyperlipidemia, anti-hyperglycemia, anti-fatigue, and anti-aging.

 

(10) These would benefit greatly on:

 

 

  • Neuroprotective & neurodegenerative activities

  • Anti-oxidative & hepatoprotective activities

  • Effect on the gastrointestinal mucosa

  • Anti-fatigue and anti-ageing activities 

  • Hypolipidemic activity

  • Hypoglycemic activity

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Reishi

Reishi is a basidiomycete, lamella less fungus belonging to the family of Polyporaceae. In nature, it grows in densely wooded mountains of high humidity and dim lighting.

 

It is rarely found since it flourishes mainly on the dried trunks of dead plum, guercus serrata, or pasonia trees. (5)

 

Reishi mushrooms are primarily composed of complex carbohydrates called polysaccharides, triterpenoids, proteins, and amino acids.

 

Studies indicate that these polysaccharides, the most active element found in Reishi, are responsible for Structural analysis of antitumor polysaccharides to strengthen the body's immune system. (6) Aside from that, Reishi mushrooms provide significant health benefits to our body, as listed below:

 

 

  • Anti-Allergic /Anti-Inf ammatory Activity

  • Sleep-promoting factor

  • Immune System

  • Healing the Liver

  • Cancer

Shiitake

The shiitake mushroom, also known as Lentinus edodes, is derived from the mushroom associated with the shii tree. Lentinula edodes is the second most popular edible mushroom in the global market. (1)

 

In carefully controlled laboratory studies, the shiitake mushroom has been shown to contain components effective in treating cancer, heart disease, and diseases caused by viral infections. Two of the most promising and effective principles isolated are lentinan and L. Edodes Mycelial culture (LEM). (2)

 

Maitake, also known as Grifola frondosa, is another major medical mushroom with numerous medicinal properties and whose primary bioactive metabolite is the D-fraction or GFP, a -glucan proteoglycan compound. Beta-glucan in Maitake can help reduce your cholesterol, improving artery functionality and overall cardiovascular health to lower your risk for heart disease. The polysaccharides in Maitake can reduce LDL (bad) cholesterol without affecting your triglyceride or HDL (good) cholesterol levels (3)

 

Maitake has been extensively studied in the past 30 years, revealing numerous medicinal properties that could provide remarkable health and other physiological benefits as listed (4) Here are a few of the benefits that Lentinan and LEM provide:

 

 

  • Anticarcinogenic and Antitumor Effects

  • Improves Appearance of Skin 

  • Cardiovascular Effects

  • Antibacterial Property

  • Antioxidant Property

  • Antifungal Property

  • Antiviral Property

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Cordyceps

Cordyceps is a medicinal mushroom that produces a vast diversity of bioactive compounds such as polysaccharides, proteoglycans, terpenoids, phenolic compounds, steroids, and lectins.

 

These compounds have a wide range of therapeutic effects and act as immunomodulatory, anticarcinogenic, antiviral, antioxidant, and anti-inflammatory agents. (7)

 

Cordyceps is a highly valued fungus in this regard which thrives at altitudes above 3,800 meters above mean sea level, in the cold, grassy, alpine meadows on the mountainous Himalayan plateau. Because of the difficulties involved in harvesting, it has been expensively priced.

 

Despite its cost and rarity, the unprecedented medicinal applications of Cordyceps have made it a highly valued staple component of traditional Chinese and Tibetan medicine. (8)

 

The bio-active compounds of this fungus contain cordycepin, cordymin, ergosterol, glycoproteins, and polysaccharides, which are considered immunity enhancers and beneficial in various treatments related to kidney, hyperglycemia, and liver damage (8).

 

Aside from that, Cordyceps provide other health benefits as listed below:

 

 

  • Inhibition of cell proliferation 

  • Thrombolytic activity

  • Anti-inflammatory property

  • Anti-oxidative property

  •  Anti-cholesterol agent

  • Fertility enhancer 

  • Anti-microbial agent 

  • Anti-diabetic property

Maitake

Maitake, also known as Grifola frondosa, is another major medical mushroom with numerous medicinal properties and whose primary bioactive metabolite is the D-fraction or GFP, a β-glucan proteoglycan compound.

 

Beta-glucan in Maitake can help reduce your cholesterol, improving artery functionality and overall cardiovascular health to lower your risk for heart disease.

 

The polysaccharides in Maitake can reduce LDL (bad) cholesterol without affecting your triglyceride or HDL (good) cholesterol levels (3) Maitake has been extensively studied in the past 30 years, revealing numerous medicinal properties that could provide remarkable health and other physiological benefits as listed (4):

 

 

  • Diabetes

  • Hypertension 

  • Hypercholesterolemia

  • Hepatitis B infection

  • Obesity

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References

Rahman T, Choudhury M. Shiitake Mushroom: A Tool of Medicine. Bangladesh Journal of Medical Biochemistry. 2013;5(1):24-32. Jong S, Birmingham J. Medicinal and Therapeutic Value of the Shiitake Mushroom. Advances in Applied Microbiology. 1993;:153-184. Ulbricht, Catherine & Weissner, Wendy & Basch, Ethan & Giese, Nicole & Hammerness, Paul & Rusie-Seamon, Erica & Varghese, Minney & Woods, Jen. (2009). Maitake mushroom (Grifola frondosa): Systematic review by the natural standard research collaboration. Journal of the Society for Integrative Oncology. 7. 66-72. 10.2310/7200.2009.0007. Molz, Patrícia & Ellwanger, Joel & Prá, Daniel & Franke, Silvia. (2014). Mushrooms: Biological characterization, antioxidant properties and interactions with human health. Batra P, Sharma A, Khajuria R. Probing Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basidiomycetes): A Bitter Mushroom with Amazing Health Benefits. International Journal of Medicinal Mushrooms. 2013;15(2):127-143. Jin X, Ruiz Beguerie J, Sze D, Chan G. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database of Systematic Reviews. 2012. SHARMA N, SHARMA V. HEALTH BENEFITS OF Cordyceps militaris: OVERVIEW. PCBMB [Internet]. 22Jul.2020 [cited 25Oct.2021];21(15-16):217-23. Available from: https://www.ikppress.org/index.php/PCBMB/article/view/5188 Das S, Masuda M, Sakurai A, Sakakibara M. Medicinal uses of the mushroom Cordyceps militaris: Current state and prospects. Fitoterapia. 2010;81(8):961-968. He X, Wang X, Fang J, Chang Y, Ning N, Guo H et al. Structures, biological activities, and industrial applications of the polysaccharides from Hericium erinaceous (Lion’s Mane) mushroom: A review. International Journal of Biological Macromolecules. 2017;97:228-237. Friedman M. ChemInform Abstract: Chemistry, Nutrition, and Health-Promoting Properties of Hericium Erinaceus (Lions Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds. ChemInform. 2015;46(41):no-no.

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