BioBDMC™50, represent specialized curcumin extracts that enhance the bioactivity of curcumin by focusing on the specific component bisdemethoxycurcumin (BDMC). This compound offers distinct advantages, particularly in antiinflammatory and antioxidant mechanisms that are not as robust in regular curcumin extracts.
Traditional Curcumin Extract Composition Traditional curcumin extracts, even those standardized to 95% curcuminoid content, typically consist of:
Curcumin I (diferuloy|methane): 75-80% of the curcuminoid content.
Curcumin II (demethoxycurcumin): 9-12%.
Curcumin III (bisdemethoxycurcumin - BDMC): 0.2-3%. In traditional extracts, BDMC comprises only a small fraction, around 0.2-3%, which limits its therapeutic potential.
At this concentration, it does not adequately inhibit the MSK1 protein, a critical mediator in the signaling pathway for pro-inflammatory cytokine transcription, reducing its overall effectiveness in managing inflammation and associated conditions.